Melanotan 2
Melanotan 2 (MT-II) is a synthetic cyclic alpha-MSH analogue and pan-melanocortin agonist studied for UV-independent tanning, libido and appetite.
Total Price
฿800
For research & laboratory use only. Not for human consumption.
Half-Life
~33 minutes
Administration Route
Subcutaneous injection
Rapid Tanning
Cyclic alpha-MSH analogue produces deep tan in 7-14 days
Libido Enhancement
MC4R activation drives arousal as side effect
Multi-Receptor Action
Binds MC1R (tan) + MC4R (arousal) + MC3R (appetite)
Effect Timeline
Initial pigmentation change; subtle darkening begins
Tan significantly visible; 3–5 UV sessions sufficient
Deep tan achieved; maintenance dose reduces UV exposure needed
Tan maintained with minimal UV; photoprotective pigment stable
Start — Days 3–7
Initial pigmentation change; subtle darkening begins
Week 2
Tan significantly visible; 3–5 UV sessions sufficient
Week 4
Deep tan achieved; maintenance dose reduces UV exposure needed
Week 8
Tan maintained with minimal UV; photoprotective pigment stable
Mechanism of Action
Scientific Research
Peptides (2000)
Urology (2000)
Why Researchers Choose Melanotan 2
Melanotan 2 (MT-II) is the reference tool compound for the melanocortin system, because a single cyclic alpha-MSH analogue engages four receptors at once. That breadth makes it a frequent subject across several research areas:
- UV-independent melanogenesis and photoprotective pigmentation via MC1R
- MC4R signalling in sexual motivation and erectile function
- Centrally mediated appetite suppression and energy-balance models
- Receptor-selectivity comparisons against the linear analogue PT-141 (bremelanotide)
- Structure-activity work on cyclic versus linear melanocortin peptides
Melanotan 2 Receptor Pharmacology
The four melanocortin receptors relevant to MT-II research and the effect each one mediates:
| Receptor | Primary Location | MT-II Effect |
|---|---|---|
| MC1R | Melanocytes, skin | Melanogenesis, photoprotection |
| MC3R | Hypothalamus, limbic | Energy balance, anti-inflammatory |
| MC4R | Hypothalamus, brainstem, spinal cord | Sexual motivation, appetite suppression, erectile function |
| MC5R | Exocrine glands, adrenal cortex | Exocrine secretion |
MC1R activity is what makes Melanotan 2 a tanning agent, while MC4R activity accounts for both the sexual response and the appetite suppression that characterise MT-II use in research.
Scientific Significance
Melanotan 2 was the compound that established MC4R as the central receptor for mammalian sexual function. A 1998 Science study showed that MT-II induced spontaneous erections in MC4R-expressing rodents and that knocking out MC4R abolished the effect. That finding led directly to three developments:
- The design of PT-141 (bremelanotide) as a selective MC4R agonist
- PT-141’s FDA approval as Vyleesi for hypoactive sexual desire disorder (HSDD)
- Sustained MC4R research across obesity, sexual dysfunction and cardiovascular regulation
As the molecule that opened up MC4R biology, Melanotan 2 holds lasting value as a research tool rather than as an approved therapeutic.
Reconstitution and Storage
Reconstitution: use bacteriostatic water; swirl gently until dissolved, do not shake. After reconstitution: keep refrigerated (2-8°C), protect from direct light, and use within 30 days.
For research purposes only. Not for human consumption.
Dosing at a Glance
Route
Subcutaneous injection
Frequency
Once daily
Typical research dose
0.25–1 mg
Opens the calculator with this peptide preselected. Research reference only.
Product FAQs
Customer Reviews
Been a solid bronze for a year. Potent MT2. Highly recommend, ordered many times. Glowing skin and a noticeable boost in libido.
Works great. And the service is the best.
Works great, it's legit. Delivery in less than 2 days to Pathum Thani. I recommend taking cetirizine 30 minutes before pinning to avoid nausea.
I arrived from Russia very fair-skinned and was badly sunburnt after my first week here. I tried another company's Melanotan and had to stop using it after a few days because it made me nauseous and the results were poor. A friend recommended Milo Lab, and after purchasing this product, the results were amazing. My skin was a golden brown, I had no side effects, and overall I felt and looked fantastic. I highly recommend Milo Lab for this product — the service and packaging were also very professional, so I could tell it's not a cheap backyard operation. From Russia with love, Zhenya.
Fantastic quality for this MT2! 4 days delivery after payment.
